In predicate abstraction, exact image computation is problematic, requiring in the worst case an exponential number of calls to a decision procedure. For this reason, software model checkers typically use a weak approximation of the image. This can result in a failure to prove a property, even given an adequate set of predicates. We present an interpolant-based method for strengthening the abstract transition relation in case of such failures. This approach guarantees convergence given an adequate set of predicates, without requiring an exact image computation. We show empirically that the method converges more rapidly than an earlier method based on counterexample analysis.